Ernesto Valverde’s side is still fighting on all three fronts and is desperate to make up for last season’s disastrous exit at the hands of Roma.
Lyon, who gave Manchester City real trouble in the group stages of the competition, have made it to the round of 16 for the first time since 2012.
Barcelona is under no illusions of the threat posed by Lyon ahead of their Champions League last-16 tie on Tuesday, says Sergio Busquets.
Lyon has proven they can mix it with Europe’s big guns, having beaten Paris Saint-Germain in Ligue 1 and Manchester City in the Champions League group stages this season.
Barca and Lyon are two of the five teams to have reached this season’s knockout phase unbeaten.
Barca coach Ernesto Valverde believes away goals could be crucial in determining who will progress to the quarter-finals.
The Spanish champions play their first game in the knockout stages of this season’s Champions League and we think there will be plenty of goals
Barcelona travels to Lyon on Tuesday evening with Ernesto Valverde’s side aiming to claim a win in the first leg of their Champions League last 16 clashes.
The Camp Nou outfit come into the game in somewhat indifferent form by their high standards.
Barca ended a run of three consecutive draws on Saturday night by beating Valladolid 1-0 in La Liga, but some doubts remain over the Spanish champions.
Team News of Lyon vs Barcelona
Samuel Umtiti could be in contention to return against his former side on Tuesday.
The France international has not played since November due to a knee problem but recently told RAC1 he is ready to return.
Valverde however says the club could exercise caution with his comeback.
Lyon captain Nabil Fekir is banned and key midfielder Tanguy Ndombele is a doubt.
Meanwhile, Barca centre-back Samuel Umtiti may return to face his old club having been sidelined since November with a knee problem, however, Thomas Vermaelen will be missing with a leg injury.
Score prediction: Lyon 1-2 Barcelona
TV channel and live stream, and online coverage
The match will be televised live on BT Sport 3.
BT Sport subscribers will be able to stream the match online via the video player and the BT Sport app.
YOU CAN FOLLOW MATCH HERE
These two have met on six occasions in the past with Barcelona sealing a 6-3 aggregate win en route to lifting the trophy during the 2008-09 season.